Life Sciences Transformational R&D Investment Fund (TRIF) Pilot
Department for Science, Innovation and TechnologyUK-wide£5m – £25m
Who can apply
Your Company To be considered eligible for the TRIF Pilot, your company must meet the following requirements: Be a UK-registered and wholly private sector business. Operate as a product developer , contract development and manufacturing organisation (CDMO) , or generics manufacturer . Provide two years of audited accounts for the applicant company or parent entity. If unavailable, you must demonstrate that the remaining project funding has been secured. Show a track record of successfully developing or manufacturing medicines or medical devices, either in the UK or internationally. Your Project To be eligible for the fund, your R&D project must: Have a total cost (including eligible capital and non-capital costs) of at least £100m . Be located in the UK . Be primarily a capital investment . Be a single company investment (as opposed to forming a partnership between companies or other types of organisations) Be dependent on the grant to proceed. Projects that would otherwise not occur, be delayed (by three years or more), scaled down, or relocated overseas without the grant may be eligible. R&D Focus Areas Applications are invited to support projects that are engaged in R&D…
What it funds
The Life Sciences Transformational R&D Investment Fund Pilot is a newly established £50 million capital grant opportunity. It aims to boost research and development (R&D) within the UK's Life Sciences sector by supporting large-scale investments focused on innovation and strengthening health resilience. The fund prioritises projects with the potential to generate economic benefits. This is a new fund that works alongside the separate Life Sciences Innovative Manufacturing Fund (LSIMF). Projects…
How to apply
The TRIF Pilot is currently accepting Expressions of Interest (EOIs). To participate, select the button above and fill out the online form through the portal. If you meet the TRIF eligibility criteria, you will receive an email, and a guidance session may be scheduled if helpful. Afterwards, you will be requested to submit Application Form 1, which serves as the formal EOI. The application process has three sections: Section 1: Application Form 1 - Expression of Interest (EOI) We will use the EOI to evaluate your eligibility and identify projects that align with the Fund’s objectives. Eligible projects will be invited to the next stage via email. Section 2: Objective 1 – innovation and health resilience assessment We will assess the health resilience and innovation benefits of your project using: (a) Application Form 1 You will need to describe the innovation and health resilience…
Last checked against the official source: 24 Aug 2026. Scheme parameters are set by the funder and can change — verify before applying, or let us do it for you.
Ask about eligibility
Plain-English answers about this scheme's published criteria — not application advice.
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